Regulators of G protein signaling (RGS) proteins as drug targets: modulating G-protein-coupled receptor (GPCR) signal transduction

J Med Chem. 2011 Nov 10;54(21):7433-40. doi: 10.1021/jm101572n. Epub 2011 Sep 29.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analgesics / administration & dosage
  • Analgesics / adverse effects
  • Animals
  • Antidepressive Agents / administration & dosage
  • Antidepressive Agents / adverse effects
  • Antiparkinson Agents / administration & dosage
  • Antiparkinson Agents / adverse effects
  • Antipsychotic Agents / administration & dosage
  • Antipsychotic Agents / adverse effects
  • Drug Interactions
  • Humans
  • Ligands
  • Molecular Targeted Therapy
  • Oligopeptides / pharmacology
  • Peptidomimetics / pharmacology
  • RGS Proteins / antagonists & inhibitors
  • RGS Proteins / genetics
  • RGS Proteins / metabolism*
  • Receptors, G-Protein-Coupled / agonists
  • Receptors, G-Protein-Coupled / antagonists & inhibitors
  • Receptors, G-Protein-Coupled / physiology*
  • Signal Transduction

Substances

  • Analgesics
  • Antidepressive Agents
  • Antiparkinson Agents
  • Antipsychotic Agents
  • Ligands
  • Oligopeptides
  • Peptidomimetics
  • RGS Proteins
  • Receptors, G-Protein-Coupled