Adjusted Wallace coefficient as a measure of congruence between typing methods

J Clin Microbiol. 2011 Nov;49(11):3997-4000. doi: 10.1128/JCM.00624-11. Epub 2011 Sep 14.


We propose a new coefficient, the adjusted Wallace coefficient (AW), and corresponding confidence intervals (CI) as quantitative measures of congruence between typing methods. The performance of the derived CI was evaluated using simulated data. Published microbial typing data were used to demonstrate the advantages of AW over the Wallace coefficient.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Typing Techniques / methods*
  • Humans
  • Methicillin-Resistant Staphylococcus aureus / genetics
  • Models, Statistical*
  • Streptococcus pyogenes / drug effects
  • Streptococcus pyogenes / genetics