PET scans in radiotherapy planning of lung cancer

Lung Cancer. 2012 Feb;75(2):141-5. doi: 10.1016/j.lungcan.2011.07.018. Epub 2011 Sep 15.


Accurate delineation of the primary tumor and of involved lymph nodes is a key requisite for successful curative radiotherapy in non-small cell lung cancer (NSCLC). In recent years, it has become clear that the incorporation of FDG PET-CT scan information into the related processes of patient selection and radiotherapy planning has lead to significant improvements for patients with NSCLC. The use of FDG PET-CT information in radiotherapy planning allows better target volume definition, reduces inter-observer variability and encourages selective irradiation of involved mediastinal lymph nodes. PET-CT also opens the door for innovative radiotherapy delivery and the development of new concepts. However, care must be taken to avoid a variety of technical pitfalls and specific education is necessary, for clinicians and physicists alike.

Publication types

  • Review

MeSH terms

  • Fluorodeoxyglucose F18
  • Humans
  • Lung Neoplasms / diagnostic imaging*
  • Lung Neoplasms / radiotherapy*
  • Multimodal Imaging / methods*
  • Positron-Emission Tomography*
  • Radiotherapy Planning, Computer-Assisted*
  • Tomography, X-Ray Computed*


  • Fluorodeoxyglucose F18