Pathophysiological distortions in time perception and timed performance

Brain. 2012 Mar;135(Pt 3):656-77. doi: 10.1093/brain/awr210. Epub 2011 Sep 15.

Abstract

Distortions in time perception and timed performance are presented by a number of different neurological and psychiatric conditions (e.g. Parkinson's disease, schizophrenia, attention deficit hyperactivity disorder and autism). As a consequence, the primary focus of this review is on factors that define or produce systematic changes in the attention, clock, memory and decision stages of temporal processing as originally defined by Scalar Expectancy Theory. These findings are used to evaluate the Striatal Beat Frequency Theory, which is a neurobiological model of interval timing based upon the coincidence detection of oscillatory processes in corticostriatal circuits that can be mapped onto the stages of information processing proposed by Scalar Timing Theory.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Attention Deficit Disorder with Hyperactivity / physiopathology
  • Attention Deficit Disorder with Hyperactivity / psychology
  • Autistic Disorder / physiopathology
  • Autistic Disorder / psychology
  • Cognition Disorders / physiopathology*
  • Cognition Disorders / psychology*
  • Humans
  • Information Theory
  • Memory / physiology
  • Neuropsychological Tests
  • Parkinson Disease / physiopathology
  • Parkinson Disease / psychology
  • Psychomotor Performance / physiology
  • Psychophysics
  • Schizophrenic Psychology
  • Time Perception / physiology*