Comparing the clinical usefulness of the Institute of Cognitive Neurology (INECO) Frontal Screening (IFS) and the Frontal Assessment Battery (FAB) in frontotemporal dementia

J Clin Exp Neuropsychol. 2011 Nov;33(9):997-1004. doi: 10.1080/13803395.2011.589375. Epub 2011 Jul 14.

Abstract

We compared the utility of two executive-function brief screening tools, the Institute of Cognitive Neurology (INECO) Frontal Screening (IFS) and the Frontal Assessment Battery (FAB), in their ability to detect executive dysfunction in a group of behavioral variant frontotemporal dementia (bv-FTD, n = 25) and Alzheimer's disease (AD, n = 25) patients in the early stages of their disease and in comparison to a group of age-, gender-, and education-matched controls (n = 26). Relative to the FAB, the IFS showed (a) better capability to differentiate between types of dementia; (b) higher sensitivity and specificity for the detection of executive dysfunction; (c) stronger correlations with standard executive tasks. We conclude that while both tools are brief and specific for the detection of early executive dysfunction in dementia, the IFS is more sensitive and specific in differentiating bvFTD from AD, and its use in everyday clinical practice can contribute to the differential diagnosis between types of dementia.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Analysis of Variance
  • Cognition Disorders / classification
  • Cognition Disorders / diagnosis*
  • Cognition Disorders / etiology*
  • Concept Formation / physiology*
  • Executive Function / physiology*
  • Female
  • Frontotemporal Dementia / complications*
  • Humans
  • Male
  • Memory, Short-Term / physiology
  • Middle Aged
  • Neuropsychological Tests
  • Psychiatric Status Rating Scales
  • ROC Curve
  • Statistics as Topic
  • Verbal Learning / physiology