Cosmeceuticals for cellulite

Semin Cutan Med Surg. 2011 Sep;30(3):167-70. doi: 10.1016/j.sder.2011.06.005.


Cellulite is characterized by alterations to the skin surface, presenting as dimpled or puckered skin of the buttocks and posterior and lateral thighs. It mainly affects women. Cellulite occurrence is believed to be due to structural, inflammatory, morphological and biochemical alterations of the subcutaneous tissue. However, its pathogenesis is not completely understood. Topical treatments for cellulite include many agents, such those that increase the microcirculation flow, agents that reduce lipogenesis and promote lipolysis, agents that restore the normal structure of dermis and subcutaneous tissue, and agents that scavenge free radicals or prevent their formation. There are many cosmetic and medical treatments for cellulite. However, there is little clinical evidence of an improvement in cellulite, and none have been shown to lead to its resolution. The successful treatment of cellulite will ultimately depend upon our understanding of the physiopathology of cellulite adipose tissue.

Publication types

  • Review

MeSH terms

  • Adipose Tissue / blood supply
  • Adipose Tissue / drug effects*
  • Adipose Tissue / pathology
  • Cosmetics / therapeutic use*
  • Female
  • Humans
  • Microcirculation / drug effects
  • Obesity / therapy*
  • Phytotherapy
  • Plant Preparations / therapeutic use*
  • Subcutaneous Tissue / drug effects*
  • Subcutaneous Tissue / pathology


  • Cosmetics
  • Plant Preparations