Treatment of hyperpigmentation

Semin Cutan Med Surg. 2011 Sep;30(3):171-5. doi: 10.1016/j.sder.2011.06.004.


Hyperpigmentation is a common dermatologic condition that is seen in all skin types but is most prominent in skin of color. In skin of color, any inflammation or injury to skin can almost immediately be accompanied by alterations in pigmentation, either hyperpigmentation or hypopigmentation. Post-inflammatory hyperpigmentation can be observed in many skin conditions including acne, eczema, and contact dermatitis and treatment can be challenging. The goal is to reduce the hyperpigmentation without causing undesirable hypopigmentation or irritation in the surrounding area. This review will discuss current research on treatments for hyperpigmentation and approaches to treating this condition.

Publication types

  • Review

MeSH terms

  • Animals
  • Dermatologic Agents / therapeutic use*
  • Humans
  • Hydroquinones / adverse effects
  • Hydroquinones / therapeutic use
  • Hyperpigmentation / drug therapy*
  • Ochronosis / chemically induced
  • Phytotherapy
  • Plant Preparations / therapeutic use*
  • Skin Pigmentation / drug effects


  • Dermatologic Agents
  • Hydroquinones
  • Plant Preparations