Minimally invasive anterior orbitotomy biopsy: finger's aspiration cutter technique (FACT)

Eur J Ophthalmol. 2012 May-Jun;22(3):309-15. doi: 10.5301/ejo.5000045.


Purpose: To evaluate aspiration cutter-assisted small-incision anterior orbitotomy.

Methods: Three patients with orbital adnexal tumors underwent orbital biopsy through a 3-mm incision in the eyelid skin (n = 2) or conjunctival fornix (n = 1). Standard aspiration cutters were introduced into anterior and posterior orbital tumors utilizing a bimanual technique. Multiple passes were made into the tumor. Fresh specimens were analyzed for adequacy prior to the end of surgery. Cytopathology, histopathology, and immunohistochemical analysis were performed.

Results: Aspiration cutter technique biopsies were diagnostic in 2 of 3 cases. Diagnoses were orbital lymphoma, metastatic endometrial adenocarcinoma, and metastatic prostate cancer. The 20-G aspiration cutter yielded the most tissue. No sutures were required for the small incisions.

Conclusions: Sutureless, aspiration cutter biopsy offered benefits commonly associated with fine needle aspiration biopsy, controlled aspiration, and enclosed mechanical cutting.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenocarcinoma / metabolism
  • Adenocarcinoma / secondary
  • Adenocarcinoma / surgery*
  • Aged, 80 and over
  • Biomarkers, Tumor / metabolism
  • Biopsy, Needle / instrumentation*
  • Female
  • Humans
  • Lymphoma / metabolism
  • Lymphoma / surgery*
  • Male
  • Middle Aged
  • Minimally Invasive Surgical Procedures*
  • Neoplasm Proteins / metabolism
  • Ophthalmologic Surgical Procedures*
  • Orbit / surgery*
  • Orbital Neoplasms / metabolism
  • Orbital Neoplasms / pathology
  • Orbital Neoplasms / secondary
  • Orbital Neoplasms / surgery*
  • Positron-Emission Tomography
  • Prospective Studies
  • Prostatic Neoplasms / metabolism
  • Prostatic Neoplasms / pathology
  • Tomography, X-Ray Computed
  • Uterine Neoplasms / metabolism
  • Uterine Neoplasms / pathology


  • Biomarkers, Tumor
  • Neoplasm Proteins