Abstract
The silver-mediated C-H trifluoromethylation of aromatic substrates using TMSCF(3) is described. The development, optimization, and scope of these transformations are reported. AgCF(3) intermediates are proposed.
© 2011 American Chemical Society
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Benzene Derivatives / chemical synthesis*
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Benzene Derivatives / chemistry
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Catalysis
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Hydrocarbons, Fluorinated / chemistry*
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Mesylates / chemistry*
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Molecular Structure
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Palladium
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Silanes / chemistry*
Substances
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Benzene Derivatives
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Hydrocarbons, Fluorinated
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Mesylates
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Silanes
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Palladium
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trimethyl(trifluoromethyl)silane
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trifluoromethanesulfonic acid