[Treatment of fresh muscle injury]

Sportverletz Sportschaden. 1990 Mar;4(1):41-4. doi: 10.1055/s-2007-993596.
[Article in German]


A prospective double-blind randomized study comparing the results of a protein-free-haemodialisate (Actovegin) with placebo was performed in 103 patients. There has been 68 patients in the haemodialysate group. In acute muscle injuries we find a dent in the muscle and a loss of function. There has been three injections in the injured muscle every three to four days. The follow up examination occurred at least three months after the beginning of the study. Full sports activity was reached in the haemodialysate group after 5.5 weeks, in the non-haemodialysate group after 8.3 weeks. There has been a significant difference in the time of rehabilitation between the shank and the thigh muscles. The results show a high statistic significance.

Publication types

  • Clinical Trial
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Athletic Injuries / therapy*
  • Case-Control Studies
  • Double-Blind Method
  • Heme / administration & dosage
  • Heme / analogs & derivatives*
  • Humans
  • Injections, Intramuscular
  • Leg Injuries / therapy*
  • Mepivacaine / administration & dosage
  • Muscles / injuries*
  • Prospective Studies
  • Randomized Controlled Trials as Topic
  • Rupture


  • Heme
  • Actovegin
  • Mepivacaine