Review
doi: 10.1016/0968-0004(90)90161-4.
Ubiquitin-conjugating enzymes: novel regulators of eukaryotic cells
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- PMID: 2193438
- DOI: 10.1016/0968-0004(90)90161-4
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Review
Ubiquitin-conjugating enzymes: novel regulators of eukaryotic cells
Trends Biochem Sci.
1990 May.
Abstract
Covalent attachment of ubiquitin to cellular proteins is essential for cell viability and is catalysed by a set of distinct ubiquitin-conjugating enzymes. Individual members of this novel enzyme family mediate strikingly diverse functions, including DNA repair, cell cycle control, selective protein degradation and essential functions of the stress response.
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