Excitable T cells: Ca(v)1.4 channel contributions and controversies

Immunity. 2011 Sep 23;35(3):315-7. doi: 10.1016/j.immuni.2011.09.001.


Store-operated CRAC channels encoded by the Orai genes mediate calcium entry in T cells. In this issue of Immunity, Omilusik et al. (2011) record Ca(V)1.4-mediated voltage-gated calcium currents in T cells and address their role for T cell development and function.

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