Acute "upside-down" visual inversion in a patient with multiple sclerosis

Neurol Sci. 2012 Jun;33(3):635-7. doi: 10.1007/s10072-011-0781-3. Epub 2011 Sep 25.


Visual and oculomotor signs and symptoms are common and well defined in patients with multiple sclerosis. On the other hand, the phenomenon of "upside-down" reversal of vision is very rare and thus not well known. The physiopathology of this phenomenon also has not been well understood. Herein, we present a female patient with multiple sclerosis, who developed acute "upside-down" visual inversion, and discuss possible mechanisms of this rare phenomenon.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Stem / pathology
  • Cerebral Ventricles / pathology
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Multiple Sclerosis / complications*
  • Vision Disorders / etiology*
  • Visual Pathways / pathology