Crystallization and preliminary X-ray crystallographic study of interleukin-8

M Auer; J Kallen; S Schleischitz; M D Walkinshaw; E Wasserbauer; G Ehn; I J Lindley

doi:10.1016/0014-5793(90)80876-k

Crystallization and preliminary X-ray crystallographic study of interleukin-8

FEBS Lett. 1990 Jun 4;265(1-2):30-2. doi: 10.1016/0014-5793(90)80876-k.

Authors

M Auer¹, J Kallen, S Schleischitz, M D Walkinshaw, E Wasserbauer, G Ehn, I J Lindley

Affiliation

¹ Sandoz Forschungsinstitut Ges.m.b.H., Vienna, Austria.

PMID: 2194830
DOI: 10.1016/0014-5793(90)80876-k

Abstract

Interleukin-8 (neutrophil-activating factor; NAP-1) has been crystallized by the vapour diffusion technique to give single crystals suitable for three-dimensional structural study at a resolution higher than 2.4 A. The crystals belong to the space group P3(1)21 or P3(2)21 and have unit cell dimensions a = b = 40.9 A, c = 90.3 A.

MeSH terms

Chemotactic Factors* / isolation & purification
Crystallization
Interleukin-8
Interleukins* / isolation & purification
X-Ray Diffraction

Substances

Chemotactic Factors
Interleukin-8
Interleukins