Long-term follow-up of polytetrafluoroethylene-covered stents implanted during percutaneous coronary intervention for management of acute coronary perforation

Catheter Cardiovasc Interv. 2012 Jul 1;80(1):53-7. doi: 10.1002/ccd.23339. Epub 2011 Dec 8.


Objective: To determine the long-term outcomes for patients receiving polytetrafluoroethylene (PTFE)-covered stents as definitive therapy, in our institution, for the management of acute coronary perforation.

Background: Coronary perforation as a complication of percutaneous coronary intervention (PCI) is associated with high morbidity and mortality. Management options included observation only or a combination of several or all of these approaches: reversal of anticoagulation, prolonged balloon inflation, deployment of a standard stent, emergent cardiac surgery, or insertion of a PTFE-covered stent.

Methods: With our IRB approval, records of 12,093 consecutive patients who received PCI during a 5-year period from January 2002 to December 2006 were reviewed and 50 patients who had coronary perforation as a complication of PCI were identified.

Results: Of the 21 patients who received a PTFE-covered stent to manage coronary perforation, one died secondary to acute thrombosis within the PTFE-covered stent in the first 24 hrs and one required emergent cardiac surgery due to continued contrast extravasation despite PTFE-covered stent deployment. The other 19 patients were followed long term (mean 55 months) and only one survivor had a potentially life-threatening outcome (subacute stent thrombosis) over that time period.

Conclusion: Utilization of a PTFE-covered stent may be a reasonable short- and long-term option to manage acute coronary perforation that occurs during PCI. On the basis of this limited experience, successful PTFE-covered stent deployment as the conclusive treatment for coronary perforation is associated with a favorable long-term event-free survival rate.

MeSH terms

  • Acute Disease
  • Angioplasty, Balloon, Coronary / adverse effects*
  • Angioplasty, Balloon, Coronary / instrumentation*
  • Angioplasty, Balloon, Coronary / mortality
  • Coated Materials, Biocompatible*
  • Coronary Angiography
  • Coronary Thrombosis / etiology
  • Coronary Thrombosis / mortality
  • Coronary Vessels / injuries
  • Delaware
  • Disease-Free Survival
  • Heart Injuries / diagnostic imaging
  • Heart Injuries / etiology
  • Heart Injuries / mortality
  • Heart Injuries / therapy*
  • Humans
  • Polytetrafluoroethylene*
  • Prosthesis Design
  • Reoperation
  • Retrospective Studies
  • Stents*
  • Time Factors
  • Treatment Outcome


  • Coated Materials, Biocompatible
  • Polytetrafluoroethylene