Transplantation of solid organs procured from influenza A H1N1 infected donors

Transpl Int. 2011 Dec;24(12):e107-10. doi: 10.1111/j.1432-2277.2011.01342.x. Epub 2011 Sep 29.

Abstract

Following the influenza A H1N1 (swine flu) pandemic, there remains little evidence informing the safety of transplanting organs from donors suspected or diagnosed with H1N1. Limited guidelines from the major transplant societies leave the use of such organs at the discretion of individual transplant centres, and practice varies considerably both nationally and internationally. We present the largest published series of outcome following transplantation of organs from H1N1 positive donors and demonstrate that these organs can be transplanted safely and with good short-term outcome. We discuss our local policy for treatment of recipients with Oseltamivir.

Publication types

  • Case Reports

MeSH terms

  • Antiviral Agents / therapeutic use
  • Humans
  • Influenza A Virus, H1N1 Subtype*
  • Influenza, Human / drug therapy
  • Influenza, Human / prevention & control
  • Influenza, Human / transmission*
  • Kidney Transplantation
  • Liver Transplantation
  • Male
  • Middle Aged
  • Oseltamivir / therapeutic use
  • Tissue Donors*
  • Tissue and Organ Procurement / methods*
  • Young Adult

Substances

  • Antiviral Agents
  • Oseltamivir