International consensus clinical practice statements for the treatment of neuropsychiatric conditions associated with epilepsy

Epilepsia. 2011 Nov;52(11):2133-8. doi: 10.1111/j.1528-1167.2011.03276.x. Epub 2011 Sep 28.


In order to address the major impact on quality of life and epilepsy management caused by associated neuropsychiatric conditions, an international consensus group of epileptologists met with the aim of developing clear evidence-based and practice-based statements to provide guidance on the management of these conditions. Using a Delphi process, this group prioritized a list of key management areas. These included: depression, anxiety, psychotic disorders, nonepileptic seizures, cognitive dysfunction, antiepileptic drug (AED)-related neurobehavioral disorders, suicidality, disorders in children and adolescents, disorders in children with intellectual disability, and epilepsy surgery. Clinical practice statements were developed for each area and consensus reached among members of the group. The assessment and management of these conditions needs to combine knowledge of psychiatric disorders, knowledge of the impact of epilepsy and its treatment on psychopathology, and an ability to deliver care within epilepsy services. The aim of these statements is to provide guidance on quality care for people with epilepsy that have a range of neuropsychiatric disorders.

Publication types

  • Practice Guideline

MeSH terms

  • Adolescent
  • Adult
  • Anxiety Disorders / complications
  • Anxiety Disorders / diagnosis
  • Anxiety Disorders / therapy
  • Child
  • Cognition Disorders / complications
  • Cognition Disorders / diagnosis
  • Cognition Disorders / therapy
  • Depressive Disorder / complications
  • Depressive Disorder / diagnosis
  • Depressive Disorder / therapy
  • Epilepsy / complications*
  • Epilepsy / psychology
  • Humans
  • Intellectual Disability / complications
  • Intellectual Disability / diagnosis
  • Intellectual Disability / therapy
  • Mental Disorders / complications*
  • Mental Disorders / therapy
  • Practice Guidelines as Topic
  • Psychotic Disorders / complications
  • Psychotic Disorders / diagnosis
  • Psychotic Disorders / therapy