Surgical outcome in children undergoing hypospadias repair under caudal epidural vs penile block

Paediatr Anaesth. 2012 Jul;22(7):707-12. doi: 10.1111/j.1460-9592.2011.03702.x. Epub 2011 Sep 29.

Abstract

Aim and objective: To evaluate the effect of penile block vs caudal epidural on the quality of analgesia and surgical outcome following hypospadias repair.

Background: Intraoperative penile engorgement because of caudal epidural may result in tension on surgical sutures and alter surgical outcome.

Methods: Fifty-four ASA I and II children were randomly allocated to group P (penile block, 0.25% bupivacaine, 0.5 mg·kg(-1) ; n = 27) and group C (caudal epidural, 0.25% bupivacaine, 0.5 ml·kg(-1) ; n = 27), respectively. Quality of analgesia was assessed by visual analog scale (VAS) score recorded at 0, 0.5, 3, 6, 12, 24 h, and once a day for the next 4 days. Duration of analgesia was calculated from the institution of block to the first analgesic demand by child or VAS > 5. Total morphine consumption in the first 48 h and oral paracetamol consumption till 5th day were recorded. Children were regularly followed up in their respective outpatient clinic for early or late complications.

Results: In group P, lower mean VAS scores were seen from 0.5 h after surgery till day 3 and analgesia lasted for significantly longer duration (82 min) when compared with caudal epidural, P < 0.001. Incidence of urethral fistula formation after primary hypospadias repair was 19.2%, and all had received caudal epidural. An increase of 27% in penile volume from baseline value was observed 10 min after caudal epidural placement, P < 0.05.

Conclusion: Penile block provided better analgesia when compared with caudal epidural in children undergoing primary hypospadias repair. Postoperative urethral fistula formation was more likely in children who received caudal epidural.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Acetaminophen / therapeutic use
  • Analgesics, Non-Narcotic / therapeutic use
  • Analgesics, Opioid / administration & dosage
  • Analgesics, Opioid / therapeutic use
  • Anesthesia, Epidural*
  • Blood Pressure / physiology
  • Child
  • Child, Preschool
  • Double-Blind Method
  • Humans
  • Hypospadias / surgery*
  • Male
  • Morphine / administration & dosage
  • Morphine / therapeutic use
  • Nerve Block*
  • Pain Measurement
  • Pain, Postoperative / drug therapy
  • Penile Erection / drug effects
  • Penis / anatomy & histology
  • Penis / physiology*
  • Penis / surgery
  • Postoperative Complications / epidemiology
  • Preanesthetic Medication
  • Treatment Outcome
  • Urinary Fistula / epidemiology
  • Urinary Fistula / etiology

Substances

  • Analgesics, Non-Narcotic
  • Analgesics, Opioid
  • Acetaminophen
  • Morphine