NetSlim: high-confidence curated signaling maps

Database (Oxford). 2011 Sep 29:2011:bar032. doi: 10.1093/database/bar032. Print 2011.


We previously developed NetPath as a resource for comprehensive manually curated signal transduction pathways. The pathways in NetPath contain a large number of molecules and reactions which can sometimes be difficult to visualize or interpret given their complexity. To overcome this potential limitation, we have developed a set of more stringent curation and inclusion criteria for pathway reactions to generate high-confidence signaling maps. NetSlim is a new resource that contains this 'core' subset of reactions for each pathway for easy visualization and manipulation. The pathways in NetSlim are freely available at

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Database Management Systems*
  • Databases, Factual*
  • Internet*
  • Signal Transduction*
  • Transforming Growth Factor beta / metabolism
  • User-Computer Interface*


  • Transforming Growth Factor beta