Relationship of biochemical parameters, BMI and blood pressure with age, gender and ethnicity of Trinidadian type 2-diabetic subjects

Arch Physiol Biochem. 2012 Feb;118(1):10-5. doi: 10.3109/13813455.2011.613482. Epub 2011 Sep 30.

Abstract

Objective: To determine the relationship of biochemical parameters, BMI and blood pressure with age, gender and ethnicity of Trinidadian type 2-diabetic subjects.

Methods: A retrospective case control study comprised of 1794 patient (740 males and 1054 females).

Results: The correlation was found for lipid profile with age and gender in diabetic subjects. There was a positive significant correlation in LDL-C values for all age groups. Serum creatinine concentrations significantly varied amongst ethnicity (p = 0.02). Of the known ethnicities, East Indians had the highest mean creatinine value (1.00 ± 0.47 mg/dl). The univariate general linear model showed that lipid profile had many associations with gender and ethnicity in type 2 diabetic subjects. LDL-C had significant differences between gender (p = 0.04) and diabetes (p = 0.01).

Conclusions: Varied lipid profile with elevated systolic blood pressure and BMI are associated in type 2 diabetic patients with respect to age, gender and ethnicity.

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Blood Glucose / analysis
  • Blood Pressure
  • Body Mass Index
  • Cholesterol, HDL / blood
  • Cholesterol, LDL / blood*
  • Cholesterol, VLDL / blood
  • Creatinine / blood*
  • Diabetes Mellitus, Type 2 / blood*
  • Diabetes Mellitus, Type 2 / ethnology
  • Diabetes Mellitus, Type 2 / physiopathology
  • Ethnicity*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Factors
  • Sex Factors
  • Trinidad and Tobago / epidemiology

Substances

  • Blood Glucose
  • Cholesterol, HDL
  • Cholesterol, LDL
  • Cholesterol, VLDL
  • Creatinine