Comparison analysis between conventional ultrasonography and ultrasound elastography of thyroid nodules

Eur J Radiol. 2012 Aug;81(8):1806-11. doi: 10.1016/j.ejrad.2011.02.070. Epub 2011 Sep 29.


Objective: To compare the effectiveness of conventional ultrasonography and ultrasound elastography in differential diagnosis of thyroid nodular diseases.

Methods: 244 patients with 291 thyroid nodules were examined by ultrasonography and ultrasound elastography respectively; the examination results were compared against pathological findings to determine the effectiveness of these two examination methods.

Results: The sensitivity and positive predictive value of conventional ultrasonography is higher than those of ultrasound elastography, but its specificity, accuracy, and negative predictive value is lower than those of the later.

Conclusions: Ultrasound elastography is superior to conventional ultrasonography in differential diagnosis of thyroid nodules. However, ultrasonography is the basis of examination; only on this basis, an additional ultrasound elastography examination could greatly improve the diagnostic rate of thyroid nodular diseases.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • China / epidemiology
  • Elasticity Imaging Techniques / methods*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Thyroid Nodule / diagnostic imaging*
  • Thyroid Nodule / epidemiology*
  • Young Adult