Selective internal radiation therapy (SIRT) in primary or secondary liver cancer

Methods. 2011 Nov;55(3):253-7. doi: 10.1016/j.ymeth.2011.09.014. Epub 2011 Sep 20.


Most patients with a history of common solid tumors will in the end develop liver metastases. Next to that, primary liver cancer, is a frequent cancer with fatal liver failure in the majority of patients. Selective internal radiation therapy (SIRT), has gradually been introduced over the recent years and is a promising, innovative albeit palliative treatment modality. The specific clinical background with regard to the indication and methodology of SIRT is presented and discussed in this paper.

Publication types

  • Review

MeSH terms

  • Animals
  • Brachytherapy / methods*
  • Humans
  • Infusions, Intra-Arterial
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / radiotherapy*
  • Neoplasms, Second Primary / diagnostic imaging
  • Neoplasms, Second Primary / radiotherapy*
  • Radionuclide Imaging
  • Yttrium Radioisotopes / administration & dosage*


  • Yttrium Radioisotopes