[Lactic acid and lactoserum in vulvovaginal infections]

Ginecol Obstet Mex. 2010 Oct;78(10):540-6.
[Article in Spanish]

Abstract

Background: The discomfort of vaginal infection symptoms is a frequent cause of medical consultation.

Objective: To determine the degree of satisfaction reported by a group of Mexican patients used the combination lactoserum lactic acid and to the relief of vulvovaginal symptoms (odor, itching and burning) or not associated with infection and the safety of that combination when used for external genital hygiene daily.

Patients and method: Clinical observational, prospective, multicenter open and made with a group of Mexican women 18-60 years of age, residents in cities across the country with some or vulvovaginal symptoms: foul odor, itching, burning. All participants were told the application, once daily, 2.5 to 5 mL of shampoo, for 14-21 days. The patients rated the presence and severity of vulvar discomfort with visual analogue scale. The data were analyzed with Statistical Analysis System statistical package version 9.1, the quantitative variables by calculating the mean +/- standard deviation, categorical variables by calculating percentages.

Results: We included 559 patients who answered the questionnaires before and after treatment. The time-use shampoo study was variable, with less than seven days were 25 patients (4.5%), 8 to 14 days 123 patients (22.0%) of 15 to 21 days, 208 patients (37.3%) and 178 patients (31.9%) used it more than 21 days. The average time elapsed since the start of treatment until the disappearance of vulvar discomfort was 4.3 days, with a SD of 3.1. In symptomatic patients the average was 4.2 days (SD 3.3), while in asymptomatic patients was 4.4 days (SD 3.0), virtually the same between groups. At the time of the final visit, 92.2% of patients reported "feeling of cleanliness" in the genital area, 91.7% "fresh feeling" and 93.9% "general feeling of wellbeing". 97.2% felt that the product is "user friendly", 94.9% considered it "soft and gentle to the skin" and 95.2% described it with "pleasing aroma".

Conclusions: Shampoo daily female external genital hygiene, the reason for this study is useful in the disappearance of the symptoms associated with infection or vulvovaginal.

Publication types

  • Clinical Trial
  • Comparative Study
  • English Abstract
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Asymptomatic Diseases
  • Combined Modality Therapy
  • Female
  • Feminine Hygiene Products
  • Humans
  • Immune Sera / administration & dosage*
  • Immunization, Passive*
  • Lactic Acid / administration & dosage
  • Lactic Acid / therapeutic use*
  • Middle Aged
  • Patient Satisfaction
  • Prospective Studies
  • Pruritus / drug therapy
  • Pruritus / therapy
  • Surveys and Questionnaires
  • Vulvovaginitis / drug therapy
  • Vulvovaginitis / therapy*
  • Young Adult

Substances

  • Immune Sera
  • lactoserum
  • Lactic Acid