Contrast-enhanced ultrasonography in the differentiation of retinal detachment and vitreous membrane in dogs and cats

J Small Anim Pract. 2011 Oct;52(10):522-30. doi: 10.1111/j.1748-5827.2011.01099.x.


Objectives: To evaluate contrast-enhanced ultrasonography (CEU) and colour Doppler imaging (CDI) for detection of persistent vascularisation in retinal detachment.

Methods: In 22 eyes, retinal detachment (n=13) and vitreous membranes (n=9) were confirmed by ophthalmological examination, during cataract surgery, by histopathology or after vitreoretinal surgery. Tentative diagnosis of retinal detachment or vitreous membrane was made using grey-scale B-mode ultrasonography. Assessment of retinal detachment was based on the presence or absence of vascularisation in the membranous structure using CDI and CEU.

Results: Sensitivity, specificity, positive-predictive value and negative-predictive value of grey-scale ultrasonography in differentiating retinal detachment from vitreous membrane were 92·3%, 66·6%, 80% and 85·7%. In 91% of eyes, colour Doppler assessment was unsuccessful due to the movement of the eye. Persistent vascularisation was demonstrated in all cases of retinal detachments with CEU. CEU was 100% accurate for detection and differentiation between retinal detachment and vitreous membrane.

Clinical significance: CEU is a useful clinical tool for the diagnosis of retinal detachment and vitreous membrane in dogs and cats.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cat Diseases / diagnostic imaging*
  • Cats
  • Contrast Media / administration & dosage
  • Diagnosis, Differential
  • Dog Diseases / diagnostic imaging*
  • Dogs
  • Female
  • Image Enhancement
  • Male
  • Prospective Studies
  • Regional Blood Flow
  • Retinal Artery
  • Retinal Detachment / diagnostic imaging
  • Retinal Detachment / veterinary*
  • Ultrasonography, Doppler, Color / veterinary*
  • Vitreous Detachment / diagnostic imaging
  • Vitreous Detachment / veterinary*


  • Contrast Media