Cerebral infarction in children with sickle cell disease: a concise overview

Hemoglobin. 2011;35(5-6):618-24. doi: 10.3109/03630269.2011.621148. Epub 2011 Oct 3.


Cerebral infarction is a common complication in sickle cell disease. Both overt and silent infarcts evident on neuroimaging have been described. In this article we overview the current knowledge of cerebral infarction in this patient population and discuss recent updates on the role of preventive intervention.

Publication types

  • Review

MeSH terms

  • Anemia, Sickle Cell / complications*
  • Anemia, Sickle Cell / therapy
  • Cerebral Infarction / diagnosis
  • Cerebral Infarction / etiology*
  • Cerebral Infarction / prevention & control
  • Child
  • Child, Preschool
  • Humans
  • Magnetic Resonance Imaging