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Review
. 2012 Jan 3;84(1):9-16.
doi: 10.1021/ac201500v. Epub 2011 Oct 24.

Increasing the Sensitivity of Magnetic Resonance Spectroscopy and Imaging

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Review

Increasing the Sensitivity of Magnetic Resonance Spectroscopy and Imaging

Andrew Webb. Anal Chem. .

Abstract

Nuclear magnetic resonance and magnetic resonance imaging are two of the most important techniques in analytical chemistry and noninvasive medical imaging, respectively. They share a common physical basis, one aspect of which is a low intrinsic sensitivity relative to complementary techniques. Encouragingly, recent advances in physics, chemistry, engineering, and data processing have enabled significant increases in sensitivity, as measured by both increased signal-to-noise and reduced data acquisition times, allowing previously unattainable data to be acquired and also new types of experiments to be designed.

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