Epidemiological characteristics of cognitive impairment of multiple sclerosis patients in a Latin American country

J Clin Exp Neuropsychol. 2011 Dec;33(10):1094-8. doi: 10.1080/13803395.2011.603690. Epub 2011 Oct 6.


We assessed cognitive performance and physical disability in 111 multiple sclerosis (MS) patients and 222 healthy controls in a multicenter study in Argentina to obtain the prevalence of cognitive impairment (CI) in a population of MS outpatients in Argentina. MS patients presented significantly lower scores in all Brief Repeatable Battery of Neuropsychology (BRB-N) tests than did the control group. The prevalence of CI was 43.2%. This study allowed us to obtain actual figures on the number of MS patients with CI in a Latin American sample. This validation is a very useful tool for clinical practice and for research studies to assess cognition in MS.

Publication types

  • Meta-Analysis

MeSH terms

  • Adult
  • Argentina / epidemiology
  • Cognition Disorders / diagnosis
  • Cognition Disorders / epidemiology*
  • Cognition Disorders / etiology*
  • Confidence Intervals
  • Disability Evaluation
  • Female
  • Humans
  • Male
  • Mental Recall / physiology
  • Middle Aged
  • Multiple Sclerosis / complications*
  • Multiple Sclerosis / epidemiology*
  • Neuropsychological Tests
  • Prevalence
  • Reproducibility of Results