Clinical assessment of occupational asthma and its differential diagnosis

Immunol Allergy Clin North Am. 2011 Nov;31(4):717-28, vi. doi: 10.1016/j.iac.2011.07.005.

Abstract

Occupational asthma (OA) is defined as asthma caused by sources and conditions attributable to a particular occupational environment and not to stimuli encountered outside the workplace. Two types of OA are distinguished based on their appearance after a latency period or not. The most frequent type appears after a latency period leading to sensitization; the clinical assessment of this type of OA is the topic of this review. The differential diagnosis of OA is also reviewed, including work-exacerbated asthma, eosinophilic bronchitis, hyperventilation syndrome, vocal cord dysfunction, bronchiolitis, and other causes of dyspnea or cough.

Publication types

  • Review

MeSH terms

  • Alveolitis, Extrinsic Allergic / diagnosis*
  • Alveolitis, Extrinsic Allergic / immunology
  • Alveolitis, Extrinsic Allergic / physiopathology
  • Asthma, Occupational / diagnosis*
  • Asthma, Occupational / immunology
  • Asthma, Occupational / physiopathology
  • Bronchial Hyperreactivity / diagnosis*
  • Bronchial Hyperreactivity / immunology
  • Bronchial Hyperreactivity / physiopathology
  • Bronchiolitis / diagnosis*
  • Bronchiolitis / immunology
  • Bronchiolitis / physiopathology
  • Diagnosis, Differential
  • Eosinophils / cytology
  • Eosinophils / metabolism
  • Forced Expiratory Volume
  • Humans
  • Immunoglobulin E / immunology
  • Occupational Exposure / prevention & control*
  • Peak Expiratory Flow Rate
  • Pulmonary Disease, Chronic Obstructive / diagnosis*
  • Pulmonary Disease, Chronic Obstructive / immunology
  • Pulmonary Disease, Chronic Obstructive / physiopathology
  • Rhinitis / diagnosis*
  • Rhinitis / immunology
  • Rhinitis / physiopathology
  • Skin Tests
  • Sputum
  • Surveys and Questionnaires

Substances

  • Immunoglobulin E