Skull base chordomas

Otolaryngol Clin North Am. 2011 Oct;44(5):1155-71. doi: 10.1016/j.otc.2011.06.002. Epub 2011 Jul 21.


Skull base chordomas are rare midline malignancies of clival origin that represent one of the most challenging skull base tumors to treat, given their location, invasiveness, potential extension around vital neurovascular structures, and high recurrence rate. Total tumor resection is the mainstay of treatment. The combination of surgery and postoperative irradiation appears to provide the best outcome.

Publication types

  • Review

MeSH terms

  • Chordoma / diagnosis
  • Chordoma / surgery*
  • Endoscopy* / adverse effects
  • Endoscopy* / methods
  • Humans
  • Magnetic Resonance Imaging
  • Postoperative Complications
  • Skull Base Neoplasms / diagnosis
  • Skull Base Neoplasms / surgery*