Increasing adherence for latent tuberculosis infection therapy with health department-administered therapy

Pediatr Infect Dis J. 2012 Feb;31(2):193-5. doi: 10.1097/INF.0b013e318236984f.


Therapy is almost universally recommended for children with latent tuberculosis infection, but long courses of therapy can decrease adherence to drug therapy. The only variable positively associated with adherence to latent tuberculosis infection therapy in our population was health department-assisted administration of drugs (odds ratio, 7.2; 95% confidence interval, 3.8-13.8).

MeSH terms

  • Adolescent
  • Antitubercular Agents / administration & dosage*
  • Child
  • Child, Preschool
  • Drug Therapy / methods*
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Latent Tuberculosis / drug therapy*
  • Male
  • Medication Adherence / statistics & numerical data*


  • Antitubercular Agents