Postmortem chemistry update part II

Int J Legal Med. 2012 Mar;126(2):199-215. doi: 10.1007/s00414-011-0614-1. Epub 2011 Oct 9.

Abstract

As a continuation of "Postmortem Chemistry Update Part I," Part II deals with molecules linked to liver and cardiac functions, alcohol intake and alcohol misuse, myocardial ischemia, inflammation, sepsis, anaphylaxis, and hormonal disturbances. A very important array of new material concerning these situations had appeared in the forensic literature over the last two decades. Some molecules, such as procalcitonin and C-reactive protein, are currently researched in cases of suspected sepsis and inflammation, whereas many other analytes are not integrated into routine casework. As in part I, a literature review concerning a large panel of molecules of forensic interest is presented, as well as the results of our own observations, where possible.

Publication types

  • Review

MeSH terms

  • Alcohol Drinking / blood
  • Alcoholism / blood*
  • Alcoholism / diagnosis
  • Anaphylaxis / blood
  • Anaphylaxis / enzymology
  • Atrial Natriuretic Factor / blood
  • Biomarkers / blood
  • C-Reactive Protein / analysis*
  • Calcitonin / blood*
  • Calcitonin Gene-Related Peptide
  • Forensic Pathology / methods*
  • Glucuronates / blood
  • Heart Diseases / blood*
  • Heart Diseases / diagnosis
  • Heart Function Tests
  • Hormones / blood
  • Humans
  • Inflammation / blood
  • Inflammation / diagnosis
  • Liver / metabolism
  • Liver Function Tests
  • Postmortem Changes*
  • Protein Precursors / blood*
  • Sepsis / blood*
  • Sepsis / diagnosis
  • Sulfuric Acid Esters / blood
  • Transferrin / analysis

Substances

  • Biomarkers
  • CALCA protein, human
  • Glucuronates
  • Hormones
  • Protein Precursors
  • Sulfuric Acid Esters
  • Transferrin
  • ethyl glucuronide
  • Atrial Natriuretic Factor
  • Calcitonin
  • C-Reactive Protein
  • Calcitonin Gene-Related Peptide
  • diethyl sulfate