Oxygen toxicity

Crit Care Clin. 1990 Jul;6(3):749-65.


The paradox of oxygen therapy is that it can be both life saving and life destroying. Considered as one of the most important drugs available to the clinician, its "dose," determined as the product of the oxygen concentration used and the duration of its use, must be titrated to avoid toxicity while still achieving adequate systemic oxygenation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Free Radicals
  • Humans
  • Oxygen / poisoning*
  • Oxygen Consumption / physiology*
  • Respiration / drug effects


  • Free Radicals
  • Oxygen