Angiographically documented hemorrhagic conversion of a left middle cerebral artery embolic stroke during intra-arterial thrombolysis

J Neurointerv Surg. 2011 Sep;3(3):246-8. doi: 10.1136/jnis.2010.003459. Epub 2010 Dec 8.

Abstract

Background and purpose: The clinical benefits of intra-arterial thrombolysis for ischemic stroke must be weighed against the risks, including hemorrhagic conversion.

Summary of case: A case of angiographically documented hemorrhagic conversion of an ischemic stroke during intra-arterial thrombolysis is presented. Discussion focuses on recognition and management of risk factors for hemorrhagic conversion during performance of stroke thrombolysis.

Conclusions: Recognition and modification of risk factors for hemorrhagic conversion may not prevent this complication during stroke thrombolysis. Identification of the angiographic appearance of hemorrhagic conversion should alert the interventionalist to the likelihood of a poor clinical outcome regardless of vessel patency status.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angiography, Digital Subtraction
  • Cerebral Angiography
  • Cerebral Hemorrhage / diagnostic imaging*
  • Cerebral Hemorrhage / etiology
  • Female
  • Fibrinolytic Agents / therapeutic use
  • Humans
  • Infarction, Middle Cerebral Artery / complications
  • Infarction, Middle Cerebral Artery / diagnostic imaging*
  • Infarction, Middle Cerebral Artery / drug therapy
  • Thrombolytic Therapy / adverse effects*
  • Thrombolytic Therapy / methods
  • Tissue Plasminogen Activator / therapeutic use
  • Tomography, X-Ray Computed

Substances

  • Fibrinolytic Agents
  • Tissue Plasminogen Activator