Perianal fistulas

Compend Contin Educ Vet. 2011 Sep;33(9):E4.


Perianal fistulas are a chronic, debilitating disease that requires lifelong monitoring and, potentially, lifelong treatment. Lesions are characterized by ulcerations with draining fistulous tracts around the anal region. Most dogs experience significant pain and discomfort with this condition. Bacterial infections are a frequent secondary problem. Definitive diagnosis is based on clinical signs, signalment, history, and a thorough examination. The most successful treatment is immunomodulatory therapy (cyclosporine with or without ketoconazole and topical tacrolimus). Perianal fistulas can be difficult to treat, frustrating both veterinarians and owners.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Bacterial Infections / diagnosis
  • Bacterial Infections / drug therapy
  • Bacterial Infections / etiology
  • Bacterial Infections / veterinary
  • Dog Diseases / diagnosis*
  • Dog Diseases / drug therapy
  • Dogs
  • Immunosuppressive Agents / therapeutic use
  • Intestinal Fistula / complications
  • Intestinal Fistula / diagnosis
  • Intestinal Fistula / drug therapy
  • Intestinal Fistula / veterinary*
  • Perianal Glands / pathology*
  • Recurrence
  • Tacrolimus / therapeutic use
  • Treatment Outcome


  • Immunosuppressive Agents
  • Tacrolimus