Automatic generation of protein structure cartoons with Pro-origami

Bioinformatics. 2011 Dec 1;27(23):3315-6. doi: 10.1093/bioinformatics/btr575. Epub 2011 Oct 12.


Summary: Protein topology diagrams are 2D representations of protein structure that are particularly useful in understanding and analysing complex protein folds. Generating such diagrams presents a major problem in graph drawing, with automatic approaches often resulting in errors or uninterpretable results. Here we apply a breakthrough in diagram layout to protein topology cartoons, providing clear, accurate, interactive and editable diagrams, which are also an interface to a structural search method.

Availability: Pro-origami is available via a web server at


Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Automation
  • Models, Molecular*
  • Protein Structure, Secondary
  • Proteins / chemistry*
  • Software


  • Proteins