Dengue nonstructural protein 1 antigen in the urine as a rapid and convenient diagnostic test during the febrile stage in patients with dengue infection

Diagn Microbiol Infect Dis. 2011 Dec;71(4):467-9. doi: 10.1016/j.diagmicrobio.2011.08.020. Epub 2011 Oct 11.

Abstract

A total of 136 matched serum and urine samples obtained from 55 patients with dengue infection and 30 other febrile illnesses were assayed for dengue nonstructural protein 1 (NS1) antigen. The urine NS1 ELISA was positive in patients with dengue fever (68.4%) and dengue hemorrhagic fever (63.9%), whereas the strip method showed a lower positive rate.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Antigens, Viral / analysis*
  • Child
  • Child, Preschool
  • Clinical Laboratory Techniques / methods*
  • Dengue / diagnosis*
  • Diagnostic Tests, Routine / methods*
  • Enzyme-Linked Immunosorbent Assay / methods
  • Female
  • Humans
  • Infant
  • Male
  • Urine / chemistry*
  • Viral Nonstructural Proteins / analysis*

Substances

  • Antigens, Viral
  • Viral Nonstructural Proteins