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. 2011 Oct 11;21(19):R811-3.
doi: 10.1016/j.cub.2011.08.045.

Membrane Trafficking: Decoding Vesicle Identity With Contrasting Chemistries

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Membrane Trafficking: Decoding Vesicle Identity With Contrasting Chemistries

Adam Frost. Curr Biol. .
Free article

Abstract

Proteins involved in membrane traffic must distinguish between different classes of vesicles. New work now shows that α-synuclein and ALPS motifs represent two extreme types of amphipathic helix that are tuned to detect both the curvature of transport vesicles as well as their bulk lipid content.

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