Ewing sarcoma is a malignant tumour of bone that is seen most often in children and young adults. The usual primary sites are the extremities, trunk, pelvis, and skull, and presentation in the mandible is rare. Cytogenetically it is characterised mainly by the translocation t(11;22)(q24;q12), which has an important role in the establishment of the clinical diagnosis. We report a 4-year-old boy with Ewing sarcoma of the mandible and the cytogenetic alterations that we found.
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