Effects of Electromagnetic Radiation From 3G Mobile Phone on Heart Rate, Blood Pressure and ECG Parameters in Rats

Toxicol Ind Health. 2012 Aug;28(7):629-38. doi: 10.1177/0748233711420468. Epub 2011 Oct 13.

Abstract

Effects of electromagnetic energy radiated from mobile phones (MPs) on heart is one of the research interests. The current study was designed to investigate the effects of electromagnetic radiation (EMR) from third-generation (3G) MP on the heart rate (HR), blood pressure (BP) and ECG parameters and also to investigate whether exogenous melatonin can exert any protective effect on these parameters. In this study 36 rats were randomized and evenly categorized into 4 groups: group 1 (3G-EMR exposed); group 2 (3G-EMR exposed + melatonin); group 3 (control) and group 4 (control + melatonin). The rats in groups 1 and 2 were exposed to 3G-specific MP's EMR for 20 days (40 min/day; 20 min active (speech position) and 20 min passive (listening position)). Group 2 was also administered with melatonin for 20 days (5 mg/kg daily during the experimental period). ECG signals were recorded from cannulated carotid artery both before and after the experiment, and BP and HR were calculated on 1st, 3rd and 5th min of recordings. ECG signals were processed and statistically evaluated. In our experience, the obtained results did not show significant differences in the BP, HR and ECG parameters among the groups both before and after the experiment. Melatonin, also, did not exhibit any additional effects, neither beneficial nor hazardous, on the heart hemodynamics of rats. Therefore, the strategy (noncontact) of using a 3G MP could be the reason for ineffectiveness; and use of 3G MP, in this perspective, seems to be safer compared to the ones used in close contact with the head. However, further study is needed for standardization of such an assumption.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analysis of Variance
  • Animals
  • Antioxidants / pharmacology
  • Blood Pressure / drug effects
  • Blood Pressure / radiation effects*
  • Body Weight / drug effects
  • Body Weight / radiation effects
  • Cell Phone*
  • Electrocardiography / drug effects
  • Electrocardiography / radiation effects*
  • Electromagnetic Radiation*
  • Heart Rate / drug effects
  • Heart Rate / radiation effects*
  • Male
  • Melatonin / pharmacology
  • Rats
  • Rats, Wistar
  • Statistics, Nonparametric

Substances

  • Antioxidants
  • Melatonin