Hyponatremia associated with bupropion

Electrolyte Blood Press. 2011 Jun;9(1):23-6. doi: 10.5049/EBP.2011.9.1.23. Epub 2011 Jun 30.


Bupropion is widely used for the treatment of depressive disorder and smoking cessation. Hyponatremia, including a syndrome of inappropriate secretion of antidiuretic hormone (SIADH), is not rare complication of treatment with antipsychotic drugs. We report a 60-year-old man who experienced severe hyponatremia after a treatment with bupropion for depressive disorder for the first time in the Korea.

Keywords: antipsychotic agents; bupropion; elderly; hyponatremia.

Publication types

  • Case Reports