A challenging epigenetic message: telomerase activity is associated with complex changes in lifestyle

Cell Biol Int. 2011 Nov;35(11):1079-83. doi: 10.1042/CBI20110046.


As an outcome of The 2009 Nobel Prize in Physiology or Medicine, a connection has been highlighted between the length of telomeres and epigenetic effects, such as intensive changes in lifestyle and nutrition as well as behavioural and psychological factors. In this review, the various elements of molecular, cell biological, nutritional and lifestyle changes are introduced and discussed.

Publication types

  • Review

MeSH terms

  • Aging / genetics
  • Aging / physiology
  • Epigenesis, Genetic*
  • Humans
  • Leukocytes, Mononuclear / cytology
  • Leukocytes, Mononuclear / enzymology
  • Life Style*
  • Stress, Psychological
  • Telomerase / genetics
  • Telomerase / metabolism*
  • Telomere / genetics
  • Telomere / metabolism*
  • Telomere Shortening*


  • Telomerase