The impressionistic landscape of meiotic recombination

Cell. 2011 Oct 14;147(2):267-70. doi: 10.1016/j.cell.2011.09.038.


Two high-resolution maps of meiotic recombination initiation sites across the genomes of budding yeast and mice illuminate broad similarities in the control of meiotic recombination in these diverse species but also highlight key differences. These studies offer new insights into the relationships between recombination, chromosome structure, and genome evolution.

Publication types

  • Research Support, N.I.H., Intramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Biological Evolution
  • Chromosomes / metabolism
  • Humans
  • Meiosis*
  • Mice
  • Recombination, Genetic*
  • Saccharomycetales / cytology*
  • Saccharomycetales / genetics
  • Saccharomycetales / metabolism