An unusual presentation of hemophilia B: pseudotumor of proximal tibia

Am J Orthop (Belle Mead NJ). 2011 Jul;40(7):E138-40.


Hemophilia is one of the most common genetically inherited causes of bleeding disorders. The usual presentation is continuous bleeding from a wound. Very seldom, it presents as a pseudotumor of bone. When left untreated, it may induce compression and pressure necrosis of adjacent structures. Careful evaluation and a high index of suspicion are usually required to arrive at the correct diagnosis. In this article, we report the case of a 10-year-old boy with hemophilia B (Christmas disease) that presented as a pseudotumor producing a large defect in the proximal tibia.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Blood Component Transfusion
  • Bone Neoplasms / diagnosis*
  • Braces
  • Child
  • Coagulants / therapeutic use
  • Diagnosis, Differential
  • Factor IX / administration & dosage
  • Hemophilia B / complications
  • Hemophilia B / diagnosis*
  • Hemophilia B / therapy
  • Hemorrhage / diagnosis*
  • Hemorrhage / etiology
  • Humans
  • Knee Joint / pathology
  • Male
  • Tibia / pathology*
  • Treatment Outcome


  • Anti-Bacterial Agents
  • Coagulants
  • Factor IX