Visceral fat volume predicts new-onset type 2 diabetes in patients with chronic hepatitis C

Diabetes Res Clin Pract. 2011 Dec;94(3):468-70. doi: 10.1016/j.diabres.2011.09.016. Epub 2011 Oct 19.

Abstract

Ninety seven patients with chronic hepatitis C (CHC) and 72 with non-alcoholic fatty liver disease (NAFLD) were enrolled. Increased visceral fat area (VFA) was associated with high values of HbA1c. The variables associated with a high risk of new-onset diabetes had a VFA>101 cm(2) in CHC, but not in NAFLD.

MeSH terms

  • Diabetes Mellitus, Type 2 / etiology*
  • Fatty Liver / complications*
  • Fatty Liver / pathology
  • Female
  • Glycated Hemoglobin A / metabolism*
  • Hepacivirus / pathogenicity*
  • Hepatitis C, Chronic / complications*
  • Hepatitis C, Chronic / pathology
  • Hepatitis C, Chronic / virology
  • Humans
  • Insulin Resistance
  • Intra-Abdominal Fat / pathology*
  • Male
  • Middle Aged
  • Non-alcoholic Fatty Liver Disease
  • Risk Factors

Substances

  • Glycated Hemoglobin A
  • hemoglobin A1c protein, human