[Validation of the Spanish version of the Chronic Obstructive Pulmonary Disease-Population Screener (COPD-PS). Its usefulness and that of FEV₁/FEV₆ for the diagnosis of COPD]

Med Clin (Barc). 2012 Nov 17;139(12):522-30. doi: 10.1016/j.medcli.2011.06.022. Epub 2011 Oct 19.
[Article in Spanish]


Background and objectives: The chronic obstructive pulmonary disease (COPD) is a highly undiagnosed disease. The use of short screening questionnaires designed to detect chronic airflow obstruction may help to the early diagnosis of COPD.

Patients and method: This was an observational, cross-sectional epidemiological study aimed to validate the translated into Spanish version of the COPD-PS questionnaire. Socio-demographic and clinical data of participants were collected, as well as their answers to the COPD-PS and EQ-5D questionnaires. The ratio FEV(1)/FEV(6) was measured with the COPD-6 device. The psychometric properties of the questionnaire and the diagnostic yield of the FEV(1)/FEV(6) ratio were analysed, both referred to the gold standard of post-bronchodilator FEV(1)/FVC < 0.7.

Results: Ten primary care centers participated in the study and included 94 controls and 79 cases with chronic airflow obstruction. Questionnaire characteristics were: feasibility, 2.3% of participants did not answer at least one item; mean time to fill the questionnaire was 47.7 seconds; 4.7% of individuals had a 0 score. Validity, moderate correlation with EQ-5D scores and moderate-high with FEV(1); the scores of COPD-PS were related to all parameters associated with COPD. A cut off of 4 units had the best sensitivity/specificity ratio and correctly classified 78% of participants. For the FEV(1)/FEV(6) ratio, a cut off of 0.75 correctly classified 85% of individuals.

Conclusions: The COPD-PS questionnaire demonstrated good psychometric properties. A cut off score of 4 has excellent predictive value. A ratio of 0.75 in the FEV(1)/FEV(6) provides an excellent correlation with the ratio FEV(1)/FVC and is useful for the identification of individuals with chronic airflow obstruction.

Publication types

  • Validation Study

MeSH terms

  • Aged
  • Albuterol / pharmacology
  • Area Under Curve
  • Bronchodilator Agents / pharmacology
  • Cross-Sectional Studies
  • Female
  • Forced Expiratory Volume* / drug effects
  • Humans
  • Male
  • Mass Screening / methods*
  • Middle Aged
  • Predictive Value of Tests
  • Psychometrics
  • Pulmonary Disease, Chronic Obstructive / diagnosis*
  • Reproducibility of Results
  • Sampling Studies
  • Sensitivity and Specificity
  • Socioeconomic Factors
  • Spain
  • Surveys and Questionnaires*
  • Translating


  • Bronchodilator Agents
  • Albuterol