Human-associated microbial signatures: examining their predictive value

Cell Host Microbe. 2011 Oct 20;10(4):292-6. doi: 10.1016/j.chom.2011.09.003.


Host-associated microbial communities are unique to individuals, affect host health, and correlate with disease states. Although advanced technologies capture detailed snapshots of microbial communities, high within- and between-subject variation hampers discovery of microbial signatures in diagnostic or forensic settings. We suggest turning to machine learning and discuss key directions toward harnessing human-associated microbial signatures.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Artificial Intelligence
  • Biodiversity*
  • Humans
  • Metagenome*
  • Predictive Value of Tests