Production of yeast killer toxin in experimentally infected animals

Mycopathologia. 1990 Jun;110(3):169-75. doi: 10.1007/BF00437542.

Abstract

The ability of a killer yeast (Pichia anomala, UCSC 25F) to produce toxin in vivo was demonstrated, for the first time, in tissues of normal and immunosuppressed experimentally infected mice by means of a fluorescent antibody technique and a killer toxin specific monoclonal antibody. The possible significance of the findings is discussed.

MeSH terms

  • Animals
  • Fluorescent Antibody Technique
  • Fungal Proteins / analysis
  • Fungal Proteins / biosynthesis*
  • Kidney / analysis
  • Kidney / microbiology
  • Killer Factors, Yeast
  • Liver / analysis
  • Liver / microbiology
  • Male
  • Mice
  • Mycoses / microbiology*
  • Mycotoxins / analysis
  • Mycotoxins / biosynthesis*
  • Pichia / metabolism*
  • Saccharomycetales / metabolism*
  • Spleen / analysis
  • Spleen / microbiology

Substances

  • Fungal Proteins
  • Killer Factors, Yeast
  • Mycotoxins