Activating L265P Mutations of the MYD88 Gene Are Common in Primary Central Nervous System Lymphoma

Acta Neuropathol. 2011 Dec;122(6):791-2. doi: 10.1007/s00401-011-0891-2. Epub 2011 Oct 22.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Biopsy
  • CARD Signaling Adaptor Proteins / genetics
  • CARD Signaling Adaptor Proteins / physiology
  • Central Nervous System Neoplasms / genetics*
  • Central Nervous System Neoplasms / pathology
  • Central Nervous System Neoplasms / physiopathology
  • Female
  • Guanylate Cyclase / genetics
  • Guanylate Cyclase / physiology
  • Humans
  • Interleukin-1 Receptor-Associated Kinases / physiology
  • Lymphoma / genetics*
  • Lymphoma / pathology
  • Lymphoma / physiopathology
  • Male
  • Middle Aged
  • Mutation / genetics*
  • Myeloid Differentiation Factor 88 / genetics*
  • Myeloid Differentiation Factor 88 / physiology
  • NF-kappa B / physiology
  • Retrospective Studies
  • Signal Transduction / genetics*
  • Signal Transduction / physiology
  • Toll-Like Receptors / physiology

Substances

  • CARD Signaling Adaptor Proteins
  • MYD88 protein, human
  • Myeloid Differentiation Factor 88
  • NF-kappa B
  • Toll-Like Receptors
  • IRAK4 protein, human
  • Interleukin-1 Receptor-Associated Kinases
  • CARD11 protein, human
  • Guanylate Cyclase