Metallo-responsive switching between hexadecameric and octameric supramolecular G-quadruplexes

Chem Commun (Camb). 2011 Dec 14;47(46):12485-7. doi: 10.1039/c1cc14965b. Epub 2011 Oct 21.

Abstract

We report the metallo-responsive high fidelity switching between hexadecameric and octameric supramolecular G-quadruplexes triggered by a change in the metal cation promoter from potassium to strontium, respectively.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • DNA / chemistry*
  • G-Quadruplexes / drug effects*
  • Potassium / pharmacology*
  • Strontium / pharmacology*

Substances

  • DNA
  • Potassium
  • Strontium