RETRACTED: MMP-9 induces CD44 cleavage and CD44 mediated cell migration in glioblastoma xenograft cells

Cell Signal. 2012 Feb;24(2):549-559. doi: 10.1016/j.cellsig.2011.10.008. Epub 2011 Oct 17.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor in Chief. On behalf the University of Illinois at Chicago, the Associate Vice Chancellor and Research Integrity Officer requested retraction of the article because of the elements listed here that were deemed false: Figure 5B, bottom row, Columns 1, 2, 4 and 5, top panel; Figure 5B, Row 1, Columns 1 and 2, bottom panel; Figure 5B, Row 2, Columns 3 and 4 bottom panel. Based on these circumstances the Editor in Chief has therefore decided to retract the paper. The corresponding author has been non-responsive to approaches from the Publisher.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Cell Line, Tumor
  • Cell Membrane / drug effects
  • Cell Membrane / genetics
  • Cell Membrane / metabolism*
  • Cell Movement / drug effects*
  • Cell Movement / genetics
  • Enzyme Activation
  • Enzyme Inhibitors / pharmacology
  • Gene Expression
  • Gene Knockdown Techniques
  • Glioblastoma / genetics
  • Glioblastoma / metabolism*
  • Glioblastoma / pathology
  • Humans
  • Hyaluronan Receptors / chemistry
  • Hyaluronan Receptors / genetics
  • Hyaluronan Receptors / metabolism*
  • Immunoprecipitation
  • Matrix Metalloproteinase 9 / deficiency
  • Matrix Metalloproteinase 9 / genetics*
  • Matrix Metalloproteinase 9 / pharmacology
  • Matrix Metalloproteinase Inhibitors
  • Mice
  • Neoplasm Invasiveness / genetics*
  • Protein Structure, Tertiary
  • Proteolysis
  • RNA, Small Interfering / genetics
  • RNA, Small Interfering / metabolism
  • Signal Transduction* / drug effects
  • Transplantation, Heterologous

Substances

  • Enzyme Inhibitors
  • Hyaluronan Receptors
  • Matrix Metalloproteinase Inhibitors
  • RNA, Small Interfering
  • Matrix Metalloproteinase 9